Obesity gene linked to 30% higher breast cancer risk

Tuesday, 24 May 2011 10:11 AM

Genetic research could help improve breast cancer treatments. A team in the US linked between the obesity associated gene (FTO) and breast cancer cells, giving those with a variant of the gene a 30% greater chance of developing breast cancer.

According to Cancer Research UK, breast cancer is the most common form of cancer in the country.

While everyone has the FTO gene, only 18% have the variant targeted by the study. It’s now hope breast cancer treatments could become more personalised, tailored to an individual’s genetic make-up, to increase survival rates.

“This is a fascinating early finding, which fits with the known connections between obesity and breast cancer,” said Virginia Kaklamani, MD, oncologist at Northwestern Memorial, co-director of the Cancer Genetics Program at the Robert H. Lurie Comprehensive Cancer Center of Northwestern University.

“This knowledge helps us better identify who is at an increased risk so one day, we can counter that risk through preventative measures and advanced screening.”

Common gene in breast cancer, heart disease

Breast cancer gene 'increases risk of heart disease'

Women with hereditary breast and ovarian cancer have genes that are also linked to a greater risk of heart disease, new research shows. A team at St. Michael's Hospital were surprised to discover the genes in question also regulate heart function.

A genetic test can help determine cancer risk

Women 'should have breast cancer test aged 35'

A genetic test at the age of 35 could predict your chances of getting breast cancer in later life. Research in the British Journal of Cancer suggests by calculating an individual’s risk could mean that fewer women would need to be screened later on.

Obesity increases risk of cancer

Breast cancer age 'determined by obesity'

Overweight women, especially those with a family history of cancer, risk developing breast cancer at an earlier age. Research from Spain found your age at your first period also plays a part in the age of first-time breast cancer patients.

Gene fault could be key to breast cancer

Targeted breast cancer treatment on test

If you have a family history of breast cancer, you hopefully know that increases your risk and regular breast checks are essential. But did you know your genetic make-up could help scientists find an effective treatment? Research is underway.

A simple routine blood test could detect breast cancer cells and help improve patient’s recovery. Image: Thinkstock

Breast cancer could be detected by blood test

A simple routine blood test could detect breast cancer cells and help improve patient’s recovery.

UK scientists pinpoint cancer-causing gene

UK scientists pinpoint cancer-causing gene

Scientists in the UK have pinpointed a key cancer-causing gene which, when overactive, can trigger an aggressive type of breast cancer to develop. This is the first time in five year that scientists have discovered a new breast cancer 'oncogene' - a cancer-causing gene.

One in eight women will get breast cancer

Risk of breast cancer increases

One in eight women will develop breast cancer, rising from one in nine, according to Cancer Research UK.New figures, published today World Cancer Day, show the lifetime risk of getting breast cancer has increased.

Researchers make breast cancer discovery

Researchers make breast cancer discovery

A new scientific study claims to have discovered a hithero unrecorded aspect of metabolic transformation in breast cancer cells – the process whereby tumour cells adapt to conditions that would kill normal cells. Researchers hope this discovery will lead to improved cancer treatments.

Smartphone addiction 'can make you stressed'

Turn off the work phone when you get home

Too much time spent working on smartphones and other mobile devices can cause a raft of health problems - people tend to maintain an awkward posture that might lead to pain in the back and neck, as well as stress-related illness.

The ultimate 15minute at-home workout

Follow these 7 steps and  you'll have the perfect at-home workout. Image: Thinkstock

Burn calories and tone up fast with this intense 15 minute workout you can do in your sitting room!